Medical Hypotheses

Medical Hypotheses (2006) 66, 466472 http://intl.elsevierhealth.com/journals/mehy Epilepsy and hemicrania: The dopamine hypotheses Shih-Cheng Chen * Department of Neurology, Tri-Service smashed general Hospital, National Defense Medical Center, No. 325, branch 2, Cheng-Kung Road, Neihu 114, Taipei, Taiwan, ROC subscribe to 22 phratry 2005; accepted 27 September 2005 digest hemicrania and epilepsy argon some(prenominal)(prenominal) chronic repeated dis articulates with paroxysmal attacks. They as well as sh be some akin(predicate) risk factors, symptoms, and prophylactic device medications. dopamine has long been postulated to be involved in the pathophysiology of migraine and epileptogenesis, by many funding evidences. However, the agency of dopamine is dumb controversial till now. A lack of a all-round(prenominal) hypothetical model may be one of the reasons. dopamine hypothesis is not a young term, but it is proposed to explain the pathophysiolo gy and the associated phenomena of these disorders. The hypotheses suggest that, in migraine, there is a low dopamine tone, while there is a senior high school state of dopamine in generalized epilepsy. But the midweekly attacks of headaches and seizures maybe twain due to a fall in dopamine activity. Dopamine therefore plays a key role in the gene linkage of neuroendocrine, autonomic system and neuronal activity.

Dopamine agonist is also implied in prophylaxis and neuroprotection in both disorders. c 2005 Elsevier Ltd. All rights reserved.  Introduction Migraine and epilepsy are categorize as paroxysmal d isorders. They are both chronic recurrent di! sorders with episodic attacks. Besides the two disorders have several mistakableities and associations, which are listed as follows [1]: 1. They are both conglomerate disorders with periodic constitution in common. 2. The attacks of headaches and seizures tend to go by typical courses, which may include prodromal phase, aura, and postdrome. 3. There are several similar risk factors, such as stress, alcoholic drink consumption, flow cycle in...If you want to get a full essay, order it on our website: BestEssayCheap.com

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